a child of 4yrs playing with painted toys since 2yrs, habitually places in the mouth and after 6hrs develops drowsiness, fever ,constipation with abdominal pain .what is the treatment of choice
High-Yield Explanation
Treatment: OF LEAD POISONING 1. Suppoive measures: gastric lavage, intravenous fluids, cardiac monitoring, etc. 2. Chelation therapy: This can be done with -- * BAL(British Anti Lewesite or dimercaprol)- 3to5mg/kg IM every 4 hrs until the urinary excretion dips below 50mcg/24hrs . Usual duration of therapy is 7to10 days. * Penicillamine -- can be given orally at a dose of 100mg/kg/day, 6th hourly for 5 days. * DMSA(Dimercapto succinic acid), or DMPS(Dimercapto propane sulfonic acid).- superior to BAL and penicillamine. REF : NARAYANAREDDY 9TH ED