Which of the following is an indication for using mifepristone?
High-Yield Explanation
Mifepristone, also known as RU486, is an antiprogestin that has been used for treatment of leiomyomas. Mifepristone diminishes leiomyoma volume by approximately half and it is effective in improving symptoms. Other uses of mifepristone: For termination of early pregnancy For emergency postcoital contraception Endometriosis Cushing's syndrome Breast cancer Other neoplasms such as meningiomas that contain glucocoicoid or progesterone receptors Ref: Hoffman B.L., Schorge J.O., Schaffer J.I., Halvorson L.M., Bradshaw K.D., Cunningham F.G., Calver L.E. (2012). Chapter 9. Pelvic Mass. In B.L. Hoffman, J.O. Schorge, J.I. Schaffer, L.M. Halvorson, K.D. Bradshaw, F.G. Cunningham, L.E. Calver (Eds), Williams Gynecology, 2e.