Which of the following causes 'no-reflow' phenomenon in acute myocardial infarction contributing to reperfusion injury?
High-Yield Explanation
Factors that contribute to reperfusion injury in myocardial infarction include the following: Mitochondrial dysfunction Myocyte hypercontracture Free radicals Platelet and complement activation Leukocyte aggregation - may occlude the microvasculature and contribute to the "no-reflow" phenomenon.