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Anaesthesia General 0e64c754

Which of the following opioids cause the least amount of nausea?

A
Fentanyl
B
Sufentanil
C
Alfentanil
D
Remifentanil
High-Yield Explanation
Intraoperative use of opioids is a well-known risk factor for postoperative nausea and vomiting. Opioids stimulate the chemoreceptor trigger zone in the area postrema of the medulla, possibly through d-receptors, and thereby lead to nausea and vomiting. When compared with approximately equipotent doses of fentanyl and sufentanil, alfentanil is associated with a lower incidence of postoperative nausea and vomiting Ref: Miller's anesthesia-7th ed, Chapter 27.

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