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Pharmacology Pharmacokinetics 0e0846cf

Which of the following is an example of a phase 1 Xenobiotic reaction? (Repeat)

A
Acetylation
B
Hydroxylation
C
Methylation
D
Glucuronidation
High-Yield Explanation
Ans: B (Hydroxylation) Ref: The Pharmacological basis of therapeutics by Goodman & Gilman - 12th ed, page no. 125Explanation:Hydroxylation is an example for phase 1 reaction while.Acetylation, glucuronidation and methylation are examples of conjugation reactions which are phase 2 reactions. (See Table 7)

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