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Pathology General 0df1e153

MHC antigens are absent on?

A
Platelet
B
Erythrocyte
C
Neutrophil
D
Monocyte
High-Yield Explanation
Ans: B. Erythrocyte(Ref: Ananthanarayan 10/e p141-143, 8/e p 132-135)MHC antigens:Absent on erythrocytes.HLA antigens:Class 1 antigens (A, B and C) - Found on surface of viually all nucleated cells.Principal antigens.Involved in graft rejection & cell-mediated cytolysis.Function as components of hormone receptors.HLA class II antigens:More restricted in distribution.Found only on cells of immune system-macrophages, dendritic cell activated T cells & mainly on B cells.

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