Thickening of the epidermis and/or dermis is
High-Yield Explanation
Thickening of epidermis or dermis is Lichenification rooks .Lichenification presents as accentuation of skin surface markings due to rubbing,thickening and hyperkeratosis of skin. Histopathology shows hyperkeratosis of all epidermal layers. The itching and rubbing can cause lichenification. Spontaneous lichenification is called lichen simplexor it can occur secondary to eczema and other inflammatory conditions. The vicious itch-scratch cycle should be broken by topic coicosteroids and sedative antihistamines Other prescriptiondrugsused to treat lichenification include: coicosteroid creams. coicosteroid injections directly into the affected skin. prescription-strength allergy drugs and antihistamines. anti-anxiety medications Ref Harrison 20th edition pg 1221