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Skin General 0d832879

Female presents with history of color change from pallor to cyanosis on exposure to cold in fingers. This condition is mostly associated with?

A
Scleroderma
B
Leukemia
C
Lung infections
D
Hepatosplenomegaly
High-Yield Explanation
A. i.e. Scleroderma Raynaud's phenomenon (i.e. cold/vibration/emotional stress-exposure Vt pallor --> cynosis & finally erythemaQ of digits, ear & tip of nose) is almost always present (along with skin sclerosis) and is often earliest featureQ of Systemic sclerosis (Scleroderm). It may precede extensive skin & internal organ involvement by week-months (in diffuse SS) to years (in limited cutaneous SS).

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