A male patient was undergoing routine health checkup and investigations when a lump was incidentally diagnosed on clinical examination. Clinician advised USG following which USG guided biopsy was done. HPE examination revealed the following diagnosis. Patient was staed on chemotherapy including a drug obtained from the given plant. What is the site of action of the drug mentioned above?
High-Yield Explanation
Vinblastine is an alkaloid derived from the periwinkle plant Vinca rosea. It has clinical activity in the treatment of Hodgkin's and non-Hodgkin's lymphomas, breast cancer, and germ cell cancer. It inhibits mitosis that is M phase of cell cycle.