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Pediatrics Hemolytic anemia 0d6852fa

In G6PD deficiency, which cells are more prone for hemolysis:

A
Older red cells
B
Young red cells
C
Reticulocytes
D
All are susceptible
High-Yield Explanation
- Mature red cells do not synthesize new proteins - Hence, as red cells ages G6PD enzyme levels fall quickly & becomes inadequate to protect against oxidant stress. - Thus, older red cells are much more prone to hemolysis than younger ones.

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