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Microbiology Misc. 0d5e65bd

All of the following are true regarding Haemophilus influenzae except

A
It can be a part of the normal flora in some persons
B
The serotyping is based on the bacterial outer membrane proteins
C
It requires Haemin and NAD for growth in culture medium
D
Type b is responsible for invasive disease
High-Yield Explanation
(B) The serotyping is based on the bacterial outer membrane proteins# Characteristics of Hemophilus influenzae: Hemophilus is a pleomorphic gram negative bacilli Hemophilus influenzae describes some of its properties Hemophilus means blood loving. This organism requires a blood containing medium for growth. Factor X and Factor V present in blood are essential for its growth (factor X acts physiologically as haemin and factor V is nicotinamide nucleotide) One important features of H. influenzae is that it does not grow properly on blood agar, because factor V is not available in blood agar as it is located inside red blood cells but when agar is heated to convert it into chocolate agar the factor V is released from R.B.C.'s> Hence H. influenzae grows better on chocolate agar> Antigenic structure: Encapsulated H. influenzae contains polysaccharide capsule. This polysaccharide capsule confers virulence Of these types of H. influenzae type b is commonly associated with invasive H. influenzae diseases such as Meningitis; Epiglottitis; Septic arthritis> Non capsulated strains of H. influenzae can colonize the upper respiratory tract of children and adults.> They lack the virulent invasiveness of encapsulated bacteria and can only cause local infection.

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