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Medicine General 0d181df4

Which of the following is not a feature of juvenile CML?

A
Thrombocytopenia
B
Lymphadenopathy
C
Presence of Philedelphia chromosome
D
High HbF
High-Yield Explanation
Philedelphia chromosome positivity is a feature of adult CML. Juvenile CML is commonly seen in children between 1-2 years of age. It is characterised by enlarged lymphnodes, spleen and liver. Lab findings includes thrombocytopenia, leukocyte count lower than classic CML, and in increase in propoion of fetal hemoglobin.

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