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Biochemistry General 0d0d06fe

Which of the functions are TRUE regarding C-terminal domain of androgen receptor protein?

A
Ligand binding
B
Increasing biological half life
C
Increasing the affinity of receptor to DNA
D
Increasing the level of transcription
High-Yield Explanation
The androgen receptor proteins contain 3 common domains: 1- Highly conserved central domain that is responsible for DNA binding 2- N-terminal region that is involved in trascriptional activation, and 3- C-terminal domain that binds ligand Ref: Harper's Illustrated Biochemistry 27th Edition, Page 477; Molecular cell biology, December 19 (12); 8383 - 8392; Urotext Basics By R. A. S. Hemat, Edition 2003, Page 68.

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