Pathology General 0ca72294

Cyclin D1 translocation is seen in ?

Follicular lymphoma

Mantle cell lymphoma

Hodgkin lymphoma

Melanoma

High-Yield Explanation

Mantle cell lymphoma is characterized by t(11,14) it places the cyclin D1 gene next to IgH enhancer gene. Among lymphomas, cyclin D1 expression is very specific for Mantle cell lymphoma.

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