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Pathology General 0c946595

Antibody associated with cold antibody immunohemolytic anemia is:

A
IgA
B
IgE
C
IgG
D
IgM
High-Yield Explanation
Cold antibody immunohemolytic anemia usually is caused by low-affinity IgM antibodies that bind to red cell membranes only at temperatures below 30°C, occurs in distal parts of the body (e.g., ears, hands, and toes) in cold weather.  Warm antibody immunohemolytic anemia is caused by immunoglobulin G (IgG) or (rarely) IgA antibodies that are active at 37°C.

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