Pharmacology General pharmacology 0c0fad6c

Which of the following statement is true regarding Fixed Dose Combination of drugs

Adverse effect of one drug may be reduced by the other drug

Two drugs with different pharmacokinetics can be combined easily

Dose of one drug can be altered independently as per requirement

Adverse effect can be ascribed to a single drug

High-Yield Explanation

Fixed Drug Combination (FDC) Two different drug moieties are combined into a single pharmaceutical formulation. * As a rule, two drugs are ideal for combination into a FDC only when they have comparable pharmacokinetics. E.g: Cotrimoxazole = Sulfamethoxazole (t1/2 -11h) + Trimethoprim(t1/2 - 10h) Syndopa = Levodopa (t1/2 -1.7h) + Carbidopa (t1/2 -2h) Ref:- HL & KK Sharma's Principles of Pharmacology 3rd Ed; Pg.No: 57-8

Which of the following statement is true regarding Fixed Dose Combination of drugs

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