Pharmacology Autacoids 0be62463 The therapeutic efficacy of antihypeensive drugs is blunted by NSAIDs because of : A Cause sodium excretion B Increase in the clearance of antihypeensive drugs C Decrease in the absorption of antihypeensive drugs D Decrease in the synthesis of vascular prostacyclin High-Yield Explanation NSAIDs inhibit Prostaglandin production including PGI2 which causes vasodilatation Ref: KD Tripathi 8th ed