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Social & Preventive Medicine General 0bb1c312

Which of the following statements about vaccines is false

A
Thiornersal is preservative in DPT vaccine
B
Magnesium chloride is stabilizer used in OPV
C
Kanamycin is preservative in measles
D
Neomycin is preservative in BCG vaccine
High-Yield Explanation
Neomycin is preservative in BCG vaccine [Ref: see below[Repeat.from Nov 08 Neomycin is used as a preservative in Measles, mumps, rubella (as well as the MMR vaccine), varicella, and poliovirus vaccines but not in BCG. About option a i.e "Thiomersal is preservative in DPT vaccine" [ Ref: Thiomersal is a mercury-based substance that has been used widely in vaccines for over 60 years as a preservative to prevent bacterial and fungal contamination, paicularly in multi-dose ls. It is used as preservative in following vaccines- DPT, Hib, Hepatitis A & B and influenza vaccines. Recently, concerns have been raised and much debate is done over the safety of thiomersal in vaccines. It is said that it being mercury based compound it can cause neurotoxicity. It is being related to autism in children. However The World Health Organization's Global Advisory Committee on Vaccine Safety (GACVS) has concluded in November 2002 that there is no evidence of toxicity in infants, children or adults exposed to thiomersal in vaccines. Still thiomersal is being replaced or reduced in vaccines.

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