All drugs used in treatment of acute gout except
High-Yield Explanation
Ans. is 'a' i.e., Allopurinol Management of gout Treatment of acute gout To provide rapid and safe pain relief Drugs used are : i) NSAIDs: These are the most frequently used drugs to treat gout because they are so well tolerated. Indomethacin is the agent of choice but other NSAIDs may be just as effective. Aspirin is usually avoided because low doses of aspirin aggravate hyperuricemia. ii) Colchicinee: Colchicine is effective but less well tolerated than NSAIDs iii) GlucocoicoidsQ: Usually reserved for patients in whom colchicines or NSAIDs are contraindicated or ineffective. Treatment of chronic gout (maintain serum urate levels at 5.0 mg/dl or less) AllopurinolQ: Xanthine oxidase inhibitor Agent of choice for most patients with gouty' Uricosuric agents Probenecid2 SulfinpyrazoneQ Treatment of gout according to the stage Asymptomatic hyperuricemia No treatment indicated, the causes should be determined and any associated problem should be addressed rigorously) Acute gouty ahritis NSAIDs or colchicines or glucocoicoid Intercritical period Prophylactic colchicines (to reduce fuher attacks) Acute tophoaecous gout Urate lowering drug (allopurinol or probenecid, sulfinpyrinazole)