Premalignant lesion for carcinoma rectum is

This autosomal dominantly inherited condition is characterised by the development of multiple rectal and colonic polyps around pubey. A colonoscopy and biopsy will confirm the diagnosis.as this condition is pre-malignant, a total colectomy must be performed; often, the rectum can be preserved, but regular flexible endoscopy and removal of polyps before they develop carcinoma are required. Ref: Bailey & Love&;s Sho Practice of Surgery,E25,Page-1228,1229