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Pathology Genetics 0b39cffe

Hereditary retinoblastomas develop due to abnormality in which of the following chromosome?

A
13ql4
B
13pl4
C
14pl3
D
14ql3
High-Yield Explanation
Ref: Robbin's Pathology, 9th ed. pg. 1339* Wilm's tumor-Aniridia complex (WAGR syndrome)11 p 13 part of (deletion of short arm of chromosome)* Retinoblastoma13q 14.11 (deletion of part of long arm of chromosome 13)* Prader-Willi syndrome Angelman syndrome15q 11-13 (deletion of part of long arm of chromosome 15)* DiGeorge's syndrome Velo-Cardio-facial syndrome22q11 (deletion of part of long arm of chromosome -22)

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