True about Hirschprung&;s disease

.It is a congenital, familial condition, occurring in newborn due to the absence of ganglion cells-- Auerbach's and Meissner's plexus in anorectum, which may extend proximally either a pa or full length of the colon. * It always involves the anus, internal sphincter and rectum (paly or entirely). * There is narrow, spasmodic, non relaxing pathological segment. * Transitional zone proximal to it contains only few ganglion cells with formation of cone. * Still proximal to it, colon is dilated enormously with hyperaemia, multiple ulcers and hyperophied circular muscle fibers. * It is one of the causes of neonatal intestinal obstruction. * Severe enterocolitis can occur which may be fatal. Perforation, peritonitis and septicaemia can occur. * Often there will be a chronic course of the disease with malnutrition, abdominal distension. ref:SRB&;s manual of surgery,ed 3,pg no 818