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Pharmacology Anti Microbial 0b1a6949

Why intravenous quinine, used in the management of complicated and severe malaria, given with 5% dextrose?

A
To avert risk of hypoglycemia
B
To avert risk of dehydration
C
To avert risk of electrolyte imbalance
D
To maintain renal blood flow
High-Yield Explanation
Ans. is 'a' i.e., To avert risk of hypoglycemia Quinine for the management of complicated and severe malaria including cerebral malaria:* Intravenous Quinine (i.v.) has been the drug of choice for cerebral malaria (falciparum malaria with impaired consciousness) and other forms of complicated malaria.* Hypoglycaemia due to hyperinsulinemia is the most important side effect due to intravenous administration of quinine, which can be prevented by infusing quinine in 5% dextrose.

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