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Pharmacology Other topics and Adverse effects 0b12a527

A 55-year-old female who is taking propanolol for the management of a cardiovascular disease experiences an acute asthmatic attack. Which of the following drugs would you prescribe to attenuate this asthmatic attack?

A
Cromolyn sodium
B
Salbutamol
C
Beclomethasone
D
Ipratropium bromide
High-Yield Explanation
(Ref: KDT 6/e p222) Inhaled b2 agonists are the agens of choice for termination of acute attack of bronchial asthma. However, as the patient is receiving b-blockers, treatment with b2 agonists will be ineffective (receptors are already blocked). Therefore, other bronchodilators like anticholinergic agents (ipratropium) or methylxanthines (theophylline) will be useful in such a case.

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