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Pathology Chemical Mediators and Regulators of Inflammation 0b06a2e7

Chemotaxis is mediated by?

A
C5a
B
IL-2
C
IFN-g
D
IL-5
High-Yield Explanation
Ans. is 'a' i.e., C5a o C5a is the most powerful chemo-attractant (chemokine).Chemotaxiso Chemotaxis is unidirectional locomotion of leukocytes towards the site of injury, oriented along a chemical gradient. This chemical gradient is created by substances called chemoattractants (chemotactic agents), which may be exogenous (bacterial products) or endogenous (C5a, LTB-4, IL-1, TNF, IL-8).

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