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Biochemistry General 0ad29da5

A 30 year old female patient complains of cough with sputum. Patient is a known case of tuberculosis and is on rifampin for the same. All of the following are true about this drug EXCEPT-

A
It inhibits transcription
B
It binds with the beta-subunit of prokaryotic RNA polymerase
C
It inhibits RNA polymerase activity
D
It binds with the alpha-subunit of prokaryotic RNA polymerase
High-Yield Explanation
Rifampin : lt is an antibiotic widely used for the treatment of  tuberculosis and leprosy. Rifampin binds with the beta-subunit of prokaryotic RNA polymerase and inhibits its activity. It inhibits transcription. Satyanarayana- Biochemistry, 3rd edition, pg-549

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