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Physiology Nervous system 0a781bd1

Which of the following statements is true about presynaptic inhibition?

A
It results due to failure of the action potential to reach the synapse
B
It occurs due to hyperpolarisation of presynaptic membrane
C
It occurs due to inhibition of release of neurotransmitter from presynaptic terminal
D
It occurs due to blockade of neurotransmitter receptors
High-Yield Explanation
presynaptic inhibition into two categories: (1) inhibition mediated by axo-axonic or dendro-axonic projections (i.e., a third pay interferes with the transmission of synaptic responses between a synaptically coupled pair of two neurons), which we may describe as heterosynaptic inhibition; and (2) inhibition mediated by the release of neurotransmitter from the active presynaptic terminal itself, or autoreceptive inhibition Ref: guyton and hall textbook of medical physiology 12 edition page number:546,547,548

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