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Biochemistry Phenylalanine and Tyrosine metabolism Detail 0a6afecc

Nitisinone is an example of

A
Enzyme activation therapy
B
Enzyme replacement therapy
C
Substrate addition therapy
D
Substrate reduction therapy
High-Yield Explanation
Nitisinone is prescribed for infantile tyrosinemia because it decreases production of the substrate (fumarylacetoacetate) for the hydrolase, thus decreasing the velocity of the reaction preventing substrate accumulation.

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