Pharmacology Cardiovascular system 098c2d63 The half-life of Amiodarone is A 3-8 min B 3-8 hours C 3-5 weeks D 3-8 weeks High-Yield Explanation After oral administration, amiodarone only has a bioavailability of 30%. It also has a half-life of approximately 50 days, so it can take weeks for therapeutic effects to appear.