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Pharmacology Anti Microbial 08da691b

True about clavulanic acid is?

A
b lactamase inhibitors
B
Extended spectrum penicillin
C
Gram negative bacteria
D
Plasmid inhibitors
High-Yield Explanation
ANSWER: (A) b lactamase inhibitorsREF: Katzung 9th ed p. 1064Beta-Lactamase Inhibitors (Clavulanic Acid, Sulbactam, & Tazobactam)[?] These substances resemble -lactam molecules but themselves have very weak antibacterial action. They are potent inhibitors of many but not all bacterial lactamases and can protect hydrolyzable penicillins from inactivation by these enzymes.[?] The indications for penicillin- -lactamase inhibitor combinations are empirical therapy for infections caused by a wide range of potential pathogens in both immunocompromised and immunocompetent patients and treatment of mixed aerobic and anaerobic infections, such as intraabdominal infections.[?] Clavulanic acid or clavulanate, usually combined Kith amoxicillin (Augmentin) or ticarcillin[?] Sulbactam, usually combined with ampicdlin[?] Tazobactam, usually combined with piperacillin

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