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Gynaecology & Obstetrics General 0898ef59

Mechanism of action of oral contraceptive pill can be all except ?

A
Hostile to sperm penetration
B
Anovulatory cycle
C
Failure of blastocyst implantation
D
Blockade of fimbrial ostia
High-Yield Explanation
Ans. is 'd' i.e., Blockade of fimbrial ostia Mechanism of action of OCPs 1nihibition of gonadotropin release from pitutary by reinforcement of normal feedback inhibition - No prevulatory LH surge - No ovulation This is the most impoant mechanism. Thickening of cervical mucus secretion (due to progesterone) - hostile to sperm penetration. Even if ovulation and feilization occur, the blastocyte fails to implant because endometrium is either hyperproliferative or hypersecretory - not suitable for nidation - Impoant in case of postcoital pill. Uterine and tubal contractions may be modified to disour feilization. Postcoital pills may dislodge a just implated blastocyte or may interfere feilization/implantation.

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