Pharmacology C.N.S 085e033e What is the drug of choice for Obsessive Compulsive Disorder? A Imipramine B Fluoxetine C Benzodiazepines D Alprazolam High-Yield Explanation Ans. (B) Fluoxetine(Ref: Harrison 17/e p2715; CMDT 2010/943; KDT 8/e p492)SSRIs are drug of choice for most of the neurotic disorders including OCD.