Pharmacology General 0858f61f

Mechanism of action of propylthiouracil in hyperthyroidism is:

Inhibition of organification of iodine

Inhibition of oxidation of iodine

Inhibition of coupling of two DIT residues

All of the above

High-Yield Explanation

Propylthiouracil, carbimazole and methimazole act by inhibiting the enzyme, thyroid peroxidase. It catalyses: Oxidation of iodine Organification Coupling

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Mechanism of action of propylthiouracil in hyperthyroidism is:

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