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Gynaecology & Obstetrics Medical Illness Complicating Pregnancy 080b5318

Itching during cholestasis of pregnancy is due retained :

A
Bilirubin
B
Bile acids
C
Alkaline phosphatase
D
Bile salts
High-Yield Explanation
Intrahepatic cholestasis and pruritus gravidarum Results from retained bile salts. Linked to high circulating levels of estrogen, which inhibit intraductal transpo of bile acids. Rx - Ursodeoxycholic acid

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