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Biochemistry General 0806a6d9

Which of the following genetic disease results from a deficiency in the liver enzyme that converts phenylalanine to tyrosine?

A
Albinism
B
Homocystinuria
C
Porphyria
D
Phenylketonuria
High-Yield Explanation
Phenylketonuria (PKU) is an inherited disorder of amino acid metabolism in which the affected individual lacks enzymes to metabolize phenylalanine. Albinism is a condition that results in a defect in tyrosine metabolism and the inability to produce melanin. Porphyria is an inherited disorder involving defects in heme synthesis. Homocystinuria is a disorder in the metabolism of homocysteine, resulting in high levels of homocysteine and methionine in plasma and urine.

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