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Medicine General 07dc3f03

Which of the following does not need treatment

A
Neuroblastoma
B
Burkitt's lymphoma
C
T cell lymphoblastic leukemia
D
AML
High-Yield Explanation
Ans. a. Neuroblastoma Though all of the four malignancies in the given options should be treated, but spontaneous regression might be seen in neuroblastoma. So, the Ans. of exclusion is neuroblastoma Tumors with Spontaneous Regression (NCR MR) NeuroblastomaQ Malignant melanomaQ ChoriocarcinomaQ RetinoblastomaQ Renal cell carcinomaQ Leukemia Treatment AML Cytarabine + Anthracycline +/- Etoposideoside CML Imatinib mesylate (DOC), Hydroxyurea, Interferon-y ALL Induction: Vincristine, prednisone, Daunorubicin, asparaginase, intrathecal Methotrexate Consolidation: Cyclophosphamide, aspraginase Maintenance: 6-mercaptopurine, Methotrexate CLL Fludarabine and Chlorambucil Burkitt's Lymphoma Treatment of Burkitt's Lymphoma in both children and adults should begin within 48 hours of diagnosis andinvolves the use of intensive combination chemotherapy regimens incorporating high doses of cyclophosphamide. Prophylactic therapy to the CNS is mandatory. Today, cure can be expected in 70-80% of both children and young adults when effective therapy is

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