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Medicine General 07d0d5d9

Which of the following is true regarding the offspring of those with Huntington’s disease

A

Half of the offspring are at risk only if the affected parent is male

B

Half of the offspring are at risk only if the affected parent is female

C

Half of the offspring are at risk for the disease

D

Half of the offspring are at risk if either parent is symptomatic for the disease before age of 30

High-Yield Explanation

As Huntington's disease is an autosomal dominant disease half of the offspring are affected . Age at which a patient becomes symptomatic is variable and has no effect on probability of transmitting the disease.

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