A 55 year old male patient complains of abnormal growth on right cheek. Patient has a habit of tobacco chewing since 30 years. Radiologic findings reveal 8x8 cm fungating mass, invading maxilla and mandible on right side. Histologic findings are suggestive of squamous cell carcinoma. Which of the following is not true regarding the treatment of this condition?
A
The drugs used are designed to block DNA replication
B
Methotrexate and 5-fluorouracil block nucleotide synthesis
C
Topoisomerase inhibitors promote the unwinding of parental DNA strands and prevent replication
D
The drugs used for cancer therapy inhibit the enzymes that participate in replication