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Microbiology General 0744c685

With reference to bacteriodes fragilis, the following statements are true, EXCEPT:

A
Bacteriodes fragilis is a frequent anaerobe isolated from clinical samples
B
Bacteriodes fragilis is not uniformly sensitive to metronidazole
C
The LPS formed by Bacteriodes fragilis is structurally and functionally different from the conventional endotoxins
D
Shock and DIC are common in bacteriodes bacterimia
High-Yield Explanation
The incidence of septic shock and DIC are unusual in patients with bacteremia caused by anaerobic bacteria such as bacteroides. Anaerobic gram negative bacteria such as bacteroides possess lipopolysaccharide (LPS) which is nearly 1000 times less potent compared to endotoxins associated with aerobic gram negative bacteria, accounting for the reason behind its low association with shock and DIC. Ref: Textbook of Microbiology, Ananthanarayan and Paniker, 7th Edition, Chapter 29, Page 268; Harrisons 16th Edition, Page 941 944.

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