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Pathology General 06fac30c

Osmotic damage is operative in all of the following complications of diabetes mellitus EXCEPT

A
The formation of cataracts
B
Insulin receptor deficiency
C
Microaneurysms in retinal vessels
D
Peripheral neuropathy
High-Yield Explanation
Osmotic damage is inoperative in insulin- receptor deficiency. Insulin-receptor deficiency is the result of an increase in adipose, which down regulates receptor synthesis, and chronic elevation of glucose (glucose toxicity), which renders the receptors less receptive to insulin.

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