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Pathology Central Nervous System 06b47f4d

Rosenthal fibres are:

A
Intranclear inclusions
B
Intracytoplasmic inclusions
C
Present extracellularly
D
Part of cell membrane
High-Yield Explanation
Ans. (b) Intracytoplasmic inclusions(Ref: R 9th/pg 1253)Rosenthal fibers-*Brightly eosinophilic structures/inclusions within cytoplasm of Q astrocytic processes*Contain two heat-shock proteins (aB-crystallin and hsp27) as well as ubiquitin Q*Seen in Alexander disease, pilocytic astrocytoma Q.

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