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Pathology Immunity 069136fe

Not true regarding NK cells is?

A
Active against malignant cells
B
Involve MHC antigen for killing micro-organisms
C
First line defense against viral infections
D
No prior sensitization required
High-Yield Explanation
Ans. (b) Involve MHC antigen for killing microorganisms (Ref: Robbins 9th/pg 192; 8th/pg 188)Natural Killer Cells Destroy virus-infected cells and tumor cells without prior exposure;NK cells do not require MHC for killing micro-organismsSurface molecules of NK cells are CD16 & CD56

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