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Pathology General 067cdd8c

Piece meal necrosis on liver biopsy is a feature of -

A
Alcoholic hepatitis
B
Indian childhood cirrhosis
C
Chronic active hepatitis
D
Primary alcoholic cirrhosis
High-Yield Explanation
Ans. is 'c' i.e., Chronic Active HepatitisPathological features of chronic active hepatitis o There is active continuous necrosis of liver cells leading to following features. Poal tracts show severe chronic inflammation with inflammatory cells extending into the liver lobules disrupting the limiting plate of hepatocytes. Piecemeal necrosis Poal fibrosis Bridging necrosis Interface hepatitisPathological features of chronic persistant hepatitis (Chronic minimal hepatitis)o Poal chronic inflammation is mild and restricted to the poal triads, there is no disruption of the limiting plates.o Little or no necrosiso Minimal fibrosis.

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