Full 2L QBank
Pharmacology General 065b1978

Acetyl salicylate & phenobarbitone are better absorbed from stomach because they are-

A
Weak acids remain non-ionic in gastric pH
B
Weak acids remain ionic in gastric pH
C
Strong acids fully ionised in gastric pH
D
Weak bases which are ionised at gastric pH
High-Yield Explanation
Ans. is 'a' i.e., Weak acids remain non-ionic at gastric pH Remember simple funda : When the medium is same drugs can cross the membrane: i) Acidic drugs can cross the membrane in acidic medium, i.e., acidic drugs are unionized at acidic pH and are lipid soluble --> so, in stomach acidic drugs are absorbed. ii) Basic drugs can cross the membrane in basic medium, i.e., basic drugs are unionized at alkaline pH and are lipid soluble --> so, in intestine basic drugs are absorbed.

Related Pharmacology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now