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Pharmacology Targeted Anticancer Drugs and Immunosuppressants 0610bf6b

Which of the following drug is used for treatment for steroid resistant Crohn's disease?

A
Leflunomide
B
Mesalamine
C
Infliximab
D
None of the above
High-Yield Explanation
Inflammatory Bowel Disease Ulcerative Colitis - Drug of choice is 5 - ASA preparation e.g. Sulfasalazine, Mesalamine - If these are not effective then steroids are used. Crohn's Disease - Drug of choice for Crohn's disease is steroids - TNF-alpha inhibitors are used in steroid resistant cases IN-Infliximab C- Ceolizumab A-Adalimumab G-Golimumab E- Etanercept - These TNF -alpha inhibitors are contraindicated in TB and Hepatitis- B.

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