Rosenthal fibres are -

Rosenthal fibers are beaded, elongated, or corkscrew-shaped intracytoplasmic inclusions measuring approximately 10-40 cm in diameter. They are identified occasionally in astrocytes associated with intense fibrillary gliosis. These have been described in reactive tissue (such as the highly gliotic tissue surrounding cysts and vascular malformations), in neoplasms (such as juvenile pilocytic astrocytomas), and Alexander disease.