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Pathology General 05cdf98d

The subtype of Hodgkin's disease, which is histogenetically distinct from all the other subtypes, is -

A
Lymphocyte predominant
B
Nodular sclerosis
C
Mixed cellularity
D
Lymphocyte depleted
High-Yield Explanation
Hodgkin's lymphoma can be divided into two groups. 1. Classical Hodgkin lymphoma This group includes Nodular sclerosis  (iii) Lymphocyte-rich Mixed cellularity    (iv) Lymphocyte-depletion The Reed-Sternberg cells have similar immunophenotype, i.e., express CD 15 and CD 30. 2. Lymphocytic predominance Hodgkin lymphoma The Reed sternberg cells express CD 20 marker, characteristic B-cell immunotype.

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