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Pharmacology General 05c19855

Sildenafil should not be used in

A
Diabetics
B
Patients on vasodilator therapy
C
Pulmonary hypertension
D
Erectile dysfunction
High-Yield Explanation
Sildenafil inhibits PDE-5 and prevents Nitric oxide (NO) degradation. Increased NO results in vasodilation. It should not be used in patients taking vosodilators as it can lead to sudden hypotension.

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