Pharmacology General 05816277

An antimetabolite which undergoes biotransformation to form an inhibitor of DNA polymerase is -

Vinablastine

Cytosine arabinoside

Methotrexate

Chlorambucil

High-Yield Explanation

Ans. is 'b' i.e., Cytosine arabinosideo Cytarabine is phosphorylated in the body to the corresponding nucleotide which inhibits DNA synthesis by inhibiting DNA polymerase.

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An antimetabolite which undergoes biotransformation to form an inhibitor of DNA polymerase is -

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