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Pharmacology General 05084280

Latest (most recent) oral direct thrombin inhibitor is -

A
Ximelagatran
B
Indraparinux
C
Dabigatran
D
Fondaparinux
High-Yield Explanation
Ans is 'c' i.e. Dabigatran o Ximelagatran was the first oral direct thrombin inhibitor approved; however, it was subsequently withdrawn from the market because of repos of liver failure. o Recently a new oral direct inhibitor, dabigatran, was approved for use in Europe for prevention of various thromboembolism in patients who have undergone hip or knee replacement surgery.

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